PDGFRA Monoclonal Antibody

SKU: BT-MCA3810

Size:100μL

Background:This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Research_area:Cardiovascular

Target_protein:PDGFRA

applications:ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:8E12F2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PDGFRA

Immunogen:Purified recombinant fragment of human PDGFRA (AA: 361-528) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):122.7kDa

UniProt accession:P16234

Synonyms:CD140A, PDGFR2, PDGFR-2, RHEPDGFRA

GeneID:5156