PDE9A Antibody - Cat. #: CSB-PA527985GA01HU

SKU: CSB-PA527985GA01HU

Size :50ul

Clone Number:

Aliases:5''-cyclic phosphodiesterase 9A antibody; cGMP specific 3' 5' cyclic phosphodiesterase type 9 antibody; FLJ90181 antibody; High affinity cGMP-specific 3'' antibody; High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A antibody; HSPDE9A2 antibody; OTTHUMP00000109399 antibody; PDE 9A antibody; Pde9a antibody; PDE9A_HUMAN antibody; Phosphodiesterase 9A antibody; phosphodiesterase PDE9A21 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O76083

Immunogen:Recombinant Human PDE9A protein

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC

Background:Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP (PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart (PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory .

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PDE9A

Research Areas:Signal transduction