PDE1B Polyclonal Antibody

SKU: BT-AP12869

Size:100μL

Background:The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research_area:Signal transduction

Target_protein:PDE1B

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q01064; Mouse: Q01065; Rat: Q01066

Synonyms:Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B ;Cam-PDE 1B;EC 3.1.4.17;63 kDa Cam-PDE

GeneID:Human: 5153