PDE1A Polyclonal Antibody

SKU: BT-AP12868

Size:100μL

Background:Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001

Research_area:Signal transduction

Target_protein:PDE1A

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P54750; Mouse: Q61481

Synonyms:Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A ;Cam-PDE 1A;EC 3.1.4.17;61 kDa Cam-PDE;hCam-1

GeneID:Human: 5136