PDCD4 antibody , Cat. # FNab06240

SKU: FNab06240

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:3B7

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA(By similarity).

Immunogen:programmed cell death 4(neoplastic transformation inhibitor)

Synonyms:H731, Nuclear antigen H731 like, PDCD4, Protein 197/15a

Observed MW:56 kDa

Uniprot ID:Q53EL6

Reactivity:Human

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:1000-1:4000; IHC: 1:20-1:200

Gene ID:27250

Research Area:Metabolism