PBEF1 Monoclonal Antibody

SKU: BT-MCA4046

Size:100μL

Background:PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

Research_area:Others

Target_protein:PBEF1

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:1D3A12

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PBEF1

Immunogen:Purified recombinant fragment of PBEF1 (aa338-479) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P43490

Synonyms:VF, PBEF, PBEF1, VISFATIN, NAMPT

GeneID:10135