PARP1 antibody , Cat. # FNab09939

SKU: FNab09939

Size:100ug

Purification:protein A+G purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:4A9

Isotype:IgG1

Storage:0.01MPBS pH 7.4,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis.

Immunogen:poly (ADP-ribose) polymerase 1

Synonyms:ADPRT, ADPRT 1, ADPRT1, pADPRT 1, PARP, PARP 1, PARP1, poly (ADP ribose) polymerase 1, Poly [ADP ribose] polymerase 1, Poly[ADP ribose] synthase 1, PPOL

Observed MW:115 kDa, 89 kDa

Uniprot ID:P09874

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IF

Recommended dilution:WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500

Gene ID:142

Research Area:Metabolism