PARP Monoclonal Antibody

SKU: BT-MCA3124

Size:100μL

Background:This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Research_area:Others

Target_protein:PARP

applications:WB, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:7A10

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PARP

Immunogen:Synthetic peptide of human PARP, conjugated to KLH.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):117kDa

UniProt accession:P09874

Synonyms:PARP, PPOL, ADPRT, ADPRT1, PARP-1, pADPRT-1, PARP1

GeneID:142