PARP-1/PARP Monoclonal Antibody

SKU: AN200038P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:PARP1

Target Synonym:SCA;ARTD;Poly[ADP-ribose] synthase;Poly ADP ribose polymerase;poly(ADP-ribose) polymerase;Poly [ADP-ribose] polymerase;NAD(+) ADP-ribosyltransferase;ADP-ribosyltransferase diphtheria toxin-like;pADPRT;ADPRT;ADPRT 1;ADPRT1;ARTD1;PARP;PARP-1;PPOL;pADPRT-1;PARP1;Cleaved PARP;ADP-ribosyltransferase diphtheria toxin-like 1;APOPAIN;NAD(+) ADP-ribosyltransferase 1;Poly [ADP-ribose] polymerase 1;Poly ADP ribose polymerase 1;poly(ADP-ribose) polymerase 1;Poly[ADP-ribose] synthase 1;SCA1;ADPRT;ADPRT 1;ADPRT1;ARTD1;pADPRT-1;PARP;PARP-1;poly(ADP-ribose) polymerase 1;PPOL

Research Areas:Cell Biology;Epigenetics and Nuclear Signaling;Metabolism;Cancer

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:WB;IHC-P;IP

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:12G6

UNIProt ID:P09874

Accession:

Background:This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Concentration:1 mg/mL

Immunogen:Recombinant Human PARP-1 / PARP protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:1000;IHC-P 1:100-1:500;IP 0.2-1 μL/mg of lysate

Calculated MW:113 kDa

ObservedMW:113 kDa