PAK2 Monoclonal Antibody

SKU: BT-MCA3569

Size:100μL

Background:PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.

Research_area:Cell Biology

Target_protein:PAK2

applications:WB, IHC, ICC

Reactivity:Human, Monkey

Clonality:Monoclonal

Clone ID:3B5

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PAK2

Immunogen:Purified recombinant fragment of PAK2 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):61kDa

UniProt accession:Q13177

Synonyms:PAK65, PAKgamma

GeneID:5062