PA Antibody - Cat. #: CSB-PA395880EA01ILR

SKU: CSB-PA395880EA01ILR

Size :50ug

Clone Number:

Aliases:PAPolymerase acidic protein antibody; EC 3.1.-.- antibody; RNA-directed RNA polymerase subunit P2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Influenza A virus (strain A/USA:Huston/AA/1945 H1N1)

UniProt ID:A4U6V9

Immunogen:Recombinant Influenza A virus Polymerase acidic protein (1-716AA)

Raised in:Rabbit

Species Reactivity:Influenza A virus

Tested Applications:ELISA

Background:Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5\' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity. In addition of its function in viral transcription, PA also plays an essential role in viral RNA synthesis and promotes the formation of the trimeric polymerase complex.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PA

Research Areas:Others