p53 Mouse mAb

SKU: EM1052

Size: 100μL

Source:Mouse

Applications:WB, IHC, IF

Reactivity:Human

Dilution:WB 1:2,000 IHC 1:200 IF 1:100-200

Immunogen:Synthetic Peptide

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):53kDa

Human_gene_id:7157

Human_swiss_prot_no:P04637

Subcellular_location:Cytoplasm; Cytoplasm. Nucleus

Other_name:Antigen NY CO 13, Cellular tumor antigen p53, FLJ92943, LFS1, Phosphoprotein p53, TP53, TRP53, tumor protein p53, Tumor suppressor p53

Background:p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro.