P38 Polyclonal Antibody

SKU: D-AB-10194L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:P38

Target Synonym:CSAID Binding Protein 1;CSAID binding protein;CSAID-binding protein;Csaids binding protein;CSBP 1;CSBP 2;CSBP;CSBP1;CSBP2;CSPB1;Cytokine suppressive anti-inflammatory drug-binding protein;EXIP;MAP kinase 14;MAP kinase MXI2;MAP kinase p38 alpha;MAPK 14;MAPK14;MAX interacting protein 2;MAX-interacting protein 2;Mitogen Activated Protein Kinase 14;Mitogen activated protein kinase p38 alpha;Mitogen-activated protein kinase 14;Mitogen-activated protein kinase p38 alpha;MK14;Mxi 2;MXI2;p38 ALPHA;p38;p38 MAP kinase;p38 MAPK;p38 mitogen activated protein kinase;p38ALPHA;p38alpha Exip;PRKM14;PRKM15;RK;SAPK2A

Research Areas:Cancer;Immunology;Signal transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IF

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P47811

Accession:

Background:MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A,p38MAPK,CSBP1,RK,p38,EXIP,Mxi2,CSBP2,PRKM14,PRKM15,CSPB1,p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.

Concentration:1 mg/mL

Immunogen:Recombinant Mouse Mapk14 protein expressed by E.coli

Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:500-1:1000;IF 1:50-1:200

Calculated MW:41kDa

ObservedMW:41kDa