P2Y12 Polyclonal Antibody

SKU: BT-AP12628

Size:100μL

Background:The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.

Research_area:Neuroscience; Signal transduction

Target_protein:P2RY12

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:P2Y purinoceptor 12

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9H244; Mouse: Q9CPV9; Rat: Q9EPX4

Synonyms:P2Y purinoceptor 12 ;P2Y12;ADP-glucose receptor;ADPG-R;P2T;AC;P2Y;AC;P2Y;cyc;P2Y12 platelet ADP receptor;P2Y;ADP;SP1999

GeneID:Human: 64805