OTC rabbit pAb

SKU: ES14359

Size: 100μL

Source:Rabbit

Applications:WB

Reactivity:Human; Mouse;Rat

Dilution:WB 1:500-2000

Immunogen:Synthesized peptide derived from human OTC AA range: 275-325

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):38kD

Human_gene_id:5009

Human_swiss_prot_no:P00480

Subcellular_location:Mitochondrion matrix .

Other_name:Ornithine carbamoyltransferase, mitochondrial (EC 2.1.3.3) (Ornithine transcarbamylase) (OTCase)

Background:This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. [provided by RefSeq, Jul 2008],