OSBPL10 antibody , Cat. # FNab06017

SKU: FNab06017

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate(PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P(PubMed:23934110)(Probable). Plays a role in negative regulation of lipid biosynthesis(PubMed:19554302). Negatively regulates APOB secretion from hepatocytes(PubMed:19554302, PubMed:22906437). Binds cholesterol and acidic phospholipids(PubMed:22906437). Also binds 25-hydroxycholesterol(PubMed:17428193). Binds phosphatidylserine(PubMed:23934110).

Immunogen:oxysterol binding protein-like 10

Synonyms:ORP10, OSBP9

Observed MW:75-80kd,64kd

Uniprot ID:Q9BXB5

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IF, IP

Recommended dilution:WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID:114884

Research Area:Metabolism