ORF1 Antibody, Biotin conjugated - Cat. #: CSB-PA327230LD01HGE

SKU: CSB-PA327230LD01HGE

Size :50ug

Clone Number:

Aliases:ORF1 antibody; Non-structural polyprotein pORF1 [Includes: Methyltransferase antibody; EC 2.1.1.- antibody; EC 2.7.7.-); Putative papain-like cysteine protease antibody; PLP antibody; EC 3.4.22.-); NTPase/helicase antibody; EC 3.6.4.-); RNA-directed RNA polymerase antibody; RdRp antibody; EC 2.7.7.48)] antibody

Product Type:Polyclonal Antibody

Immunogen Species:Hepatitis E virus genotype 1 (isolate Homo sapiens (Human)/Pakistan/Sar-55) (HEV-1)

UniProt ID:P33424

Immunogen:Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 protein (60-240AA)

Raised in:Rabbit

Species Reactivity:Hepatitis E virus genotype 1

Tested Applications:ELISA

Background:Methyltransferase displays a cytoplasmic capping enzyme activity. This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus. The enzymatic reaction involves a covalent link between 7-methyl-GMP and the methyltransferase, whereas eukaryotic capping enzymes form a covalent complex only with GMP. Methyltransferase catalyzes transfer of a methyl group from S-adenosylmethionine to GTP and GDP to yield m7GTP or m7GDP. GMP, GpppG, and GpppA were poor substrates for the methyltransferase. This enzyme also displays guanylyltransferase activity to form a covalent complex, methyltransferase-m7GMP, from which 7-methyl-GMP is transferred to the mRNA to create the cap structure. Cap analogs such as m7GTP, m7GDP, et2m7GMP, and m2et7GMP inhibit the methyltransferase reaction (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ORF1

Research Areas:Others