OAS2 Antibody - Cat. #: CSB-PA780177

SKU: CSB-PA780177

Size :50ul

Clone Number:

Aliases:(2-5'')oligo(A) synthase 2 antibody; (2-5')oligo(A) synthetase 2 antibody; 2''-5''-oligoadenylate synthase 2 antibody; 2'-5'-oligoadenylate synthetase 2 antibody; 2'-5'-oligoadenylate synthetase 2; 69/71kDa antibody; 2-5A synthase 2 antibody; 2-5A synthetase 2 antibody; 2-prime; 5-prime-oligoadenylate synthetase 2 antibody; 2-prime; 5-prime-oligoadenylate synthetase 2; 69-KD antibody; MGC78578 antibody; OAS2 antibody; OAS2_HUMAN antibody; p69 antibody; p69 OAS / p71 OAS antibody; p69OAS / p71OAS antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P29728

Immunogen:Fusion protein of Human OAS2

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000

Background:This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:OAS2

Research Areas:Epigenetics and Nuclear Signaling;Immunology