NPR1 Polyclonal Antibody

SKU: E-AB-15504

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: NPR1

Target Synonym: ANP-A;ANPa;ANPR-A;ANPRA;ANPRA;Atrial natriuretic peptide A type receptor;Atrial natriuretic peptide receptor 1;Atrial natriuretic peptide receptor A;Atrial natriuretic peptide receptor type A;Atrionatriuretic peptide receptor A;GC A;GC-A;Guanylate cyclase A;Guanylate cyclase;GUC2A;GUCY2A;Natriuretic peptide A type receptor;Natriuretic peptide receptor A/guanylate cyclase A;NPR-A;NPR1;NPRA

Research Areas: Cancer;Cardiovascular;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P16066

Accession:

Background: Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms . The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).

Concentration: 0.4 mg/mL

Immunogen: Synthetic peptide of human NPR1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:25-1:100

Calculated MW:

ObservedMW: