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Gene Bio Systems

NPR1 Antibody - Cat. #: CSB-PA934625

NPR1 Antibody - Cat. #: CSB-PA934625

CSB-PA934625

£287.00 GBP
£287.00 GBP
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Size :50ul

Clone Number:

Aliases:ANP-A antibody; ANPa antibody; ANPR-A antibody; ANPRA antibody; ANPRA_HUMAN antibody; Atrial natriuretic peptide A type receptor antibody; Atrial natriuretic peptide receptor 1 antibody; Atrial natriuretic peptide receptor A antibody; Atrial natriuretic peptide receptor type A antibody; Atrionatriuretic peptide receptor A antibody; GC A antibody; GC-A antibody; Guanylate cyclase A antibody; Guanylate cyclase antibody; GUC2A antibody; GUCY2A antibody; Natriuretic peptide A type receptor antibody; Natriuretic Peptide Receptor A antibody; Natriuretic peptide receptor A/guanylate cyclase A antibody; NPR-A antibody; NPR1 antibody; NPRA antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P16066

Immunogen:Synthetic peptide of Human NPR1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:25-1:100

Background:Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms . The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NPR1

Research Areas:Cardiovascular;Signal transduction

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