NLTP Rabbit Polyclonal Antibody

SKU: BT-AP03830

Size:100μL

Background:This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2)| as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein| and the transcript initiated from the distal promoter encodes the shorter SCP2 protein| with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids| while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism| and may play a role in Zellweger syndrome| in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants| some encoding different isoforms.

Research_area:Cancer; Metabolism; Signal transduction

Target_protein:SCP2

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:NLTP

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):60170

UniProt accession:Human: P22307; Mouse: P32020; Rat: P11915

Synonyms:NLTP

GeneID:Human: 6342; Mouse: 20280; Rat: 25541