NLRP10 Polyclonal Antibody

SKU: E-AB-16648

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: NLRP10

Target Synonym: CLR11.1;NACHT;leucine rich repeat and PYD containing 10;NACHT;LRR and PYD domains containing protein 10;NACHT;LRR and PYD domains-containing protein 10;NAL10;NALP10;NLR family;pyrin domain containing 10;Nlrp10;NOD8;Nucleotide-binding oligomerization domain protein 8;Nucleotide-binding oligomerization domain;leucine rich repeat and pyrin domain containing 10;PAN5;PYNOD

Research Areas: Cell biology;Immunology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q86W26

Accession:

Background: Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.

Concentration: 1.2 mg/mL

Immunogen: Synthetic peptide of human NLRP10

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: