NKX3-1 Antibody - Cat. #: CSB-PA143729

SKU: CSB-PA143729

Size :100ul

Clone Number:

Aliases:BAPX 2 antibody; BAPX2 antibody; Homeobox protein NK-3 homolog A antibody; Homeobox protein Nkx 3.1 antibody; Homeobox protein Nkx-3.1 antibody; Homeobox protein Nkx3.1 antibody; NK homeobox (Drosophila) family 3 A antibody; NK homeobox family 3 A antibody; NK homeobox, family 3, member A antibody; NK3 homeobox 1 antibody; NK3 transcription factor homolog A antibody; NK3 transcription factor related locus 1 antibody; NKX 3 antibody; Nkx 3.1 antibody; NKX 3A antibody; NKX3 1 antibody; NKX3 antibody; Nkx3-1 antibody; NKX3.1 antibody; Nkx3.1, mouse, homolog of antibody; NKX31_HUMAN antibody; NKX3A antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q99801

Immunogen:Synthesized peptide derived from N-terminal of Human NKX3.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.

Cai Bowen, Cancer Res., Jan 2007; 67: 455 - 464.
Xiang Li, Mol. Cell. Biol., Apr 2006; 26: 3008 - 3017.
Ekatherine Asatiani, Cancer Res., Feb 2005; 65: 1164 - 1173.
Carlise R. Bethel, Cancer Res., Nov 2006; 66: 10683 - 10690.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NKX3-1

Research Areas:Epigenetics and Nuclear Signaling