NFATC1 Antibody - Cat. #: CSB-PA239200

SKU: CSB-PA239200

Size :50ul

Clone Number:

Aliases:cytoplasmic 1 antibody; MGC138448 antibody; NF ATc antibody; NF ATc1 antibody; NF-ATc antibody; NF-ATc1 antibody; NF-ATc1.2 antibody; NFAC1_HUMAN antibody; NFAT 2 antibody; NFAT transcription complex cytosolic component antibody; NFATC 1 antibody; NFATc antibody; NFATc1 antibody; Nuclear factor of activated T cells cytoplasmic 1 antibody; Nuclear factor of activated T cells cytoplasmic calcineurin dependent 1 antibody; Nuclear factor of activated T cells cytosolic component 1 antibody; nuclear factor of activated T-cells 'c' antibody; Nuclear factor of activated T-cells antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95644

Immunogen:Fusion protein of Human NFATC1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100

Background:The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NFATC1

Research Areas:Epigenetics and Nuclear Signaling;Cardiovascular;Immunology;Signal transduction