NFAT2 Polyclonal Antibody

SKU: E-AB-60332

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:NFAT2

Target Synonym:NF-ATC;NF-ATc1.2;NFAT2;NFATc;NFATC1

Research Areas:Cancer;Cardiovascular;Epigenetics and Nuclear Signaling;Immunology;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:O95644

Accession:

Background:The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Concentration:1mg/mL

Immunogen:Recombinant fusion protein of human NFAT2 (NP_765978.1).

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification method:Affinity purification

Dilution:WB 1:500-1:3000;IHC 1:50-1:200

Calculated MW:38kDa/74- 88kDa/100-101kDa

ObservedMW:78kDa