NEUROD1 Antibody, HRP conjugated - Cat. #: CSB-PA615700LB01HU

SKU: CSB-PA615700LB01HU

Size :50ug

Clone Number:

Aliases:atonal antibody; basic helix loop helix transcription factor antibody; BETA 2 antibody; Beta cell E box transactivator 2 antibody; BETA2 antibody; BHF 1 antibody; BHF1 antibody; bHLHa3 antibody; class A basic helix loop helix protein 3 antibody; Class A basic helix-loop-helix protein 3 antibody; MODY 6 antibody; MODY6 antibody; NDF1_HUMAN antibody; NeuroD antibody; NeuroD1 antibody; Neurogenic differentiation 1 antibody; Neurogenic differentiation factor 1 antibody; neurogenic helix loop helix protein NEUROD antibody; Neuronal differentiation 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13562

Immunogen:Recombinant Human Neurogenic differentiation factor 1 protein (154-356AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5\'-CANNTG-3\'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NEUROD1

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cardiovascular; Metabolism