NEK3 Polyclonal Antibody

SKU: BT-AP11800

Size:100μL

Background:This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.

Research_area:Cancer; Signal transduction

Target_protein:NEK3

applications:WB, ELISA

Reactivity:Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Serine/threonine-protein kinase Nek3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P51956; Mouse: Q9R0A5

Synonyms:Serine/threonine-protein kinase Nek3 ;EC 2.7.11.1;HSPK 36;Never in mitosis A-related kinase 3;NimA-related protein kinase 3

GeneID:Human: 4752