GeneBio Systems
NEFL Polyclonal Antibody
NEFL Polyclonal Antibody
SKU:E-AB-60048
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Size::120μL
Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date:12 months
Category ID_II:Primary Antibodies
Category ID_III:Polyclonal Antibodies
Abbreviation:NEFL
Target Synonym:NEFL;CMT1F;CMT2E;NF-L;NF68;NFL;PPP1R110
Research Areas:Cancer;Developmental Biology;Neuroscience;Signal Transduction;Stem Cells
Conjugation:Unconjugated
Host:Rabbit
Species reactivity:Human;Mouse;Rat
Application:IHC;IF
Isotype:IgG
Clonality:Polyclonal
Clone NO.:
UNIProt ID:P07196
Accession:
Background:Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Concentration:1mg/mL
Immunogen:Recombinant fusion protein of human NEFL (NP_006149.2).
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification method:Affinity purification
Dilution:IHC 1:50-1:200;IF 1:50-1:200
Calculated MW:
ObservedMW:
