NDN Antibody, FITC conjugated - Cat. #: CSB-PA859515LC01HU

SKU: CSB-PA859515LC01HU

Size :50ug

Clone Number:

Aliases:HsT16328 antibody; NDN antibody; NECD_HUMAN antibody; Necdin antibody; Necdin homolog antibody; Necdin MAGE family member antibody; necdin related protein antibody; PWCR antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q99608

Immunogen:Recombinant Human Necdin protein (1-98AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NDN

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Cell biology