NCR2 Antibody - Cat. #: CSB-PA551201

SKU: CSB-PA551201

Size :50ul

Clone Number:

Aliases:Activating NK receptor NKp44 antibody; CD336 antibody; CD336 antigen antibody; dJ149M18.1 antibody; LY95 antibody; Lymphocyte antigen 95 (activating NK receptor, NK p44) antibody; Lymphocyte antigen 95 homolog (activating NK receptor, NK p44) antibody; Lymphocyte antigen 95 homolog antibody; Lymphocyte antigen 95, mouse, homolog of antibody; Natural cytotoxicity triggering receptor 2 antibody; Natural killer cell p44 related protein antibody; Natural killer cell p44-related protein antibody; NCR2 antibody; NCTR2_HUMAN antibody; NK cell activating receptor (NKp44) antibody; NK cell activating receptor antibody; NK cell-activating receptor antibody; NK p44 antibody; NK-p44 antibody; NKp44 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O95944

Immunogen:Synthetic peptide of Human NCR2

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:50-1:200

Background:Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the NCR2 gene. NCR2 has also been designated as CD336 (cluster of differentiation 336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NCR2

Research Areas:Immunology;Signal transduction