N Antibody - Cat. #: CSB-PA321352YA01RAI

SKU: CSB-PA321352YA01RAI

Size :50ug

Clone Number:

Aliases:N antibody; Nucleoprotein antibody; NP antibody; Nucleocapsid protein antibody; Protein N antibody

Product Type:Polyclonal Antibody

Immunogen Species:Rabies virus

UniProt ID:P15197

Immunogen:Recombinant Rabies virus Nucleoprotein protein (1-450AA)

Raised in:Rabbit

Species Reactivity:Rabies virus

Tested Applications:ELISA

Background:Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it\\\'s own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases .

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:N

Research Areas:Others