MYST1 Monoclonal Antibody

SKU: BT-MCA2760

Size:100μL

Background:MYST1 (MYST histone acetyltransferase 1, MOF) belongs to the MYST family of histone acetyltransferases, which are employed in the cell to bring about transcriptional regulation. The MYST family includes MYST1, is named for the founding members MOZ, yeast YBF2 and SAS2, and TIP60. All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein- protein interactions and targeting transcriptional regulators to chromatin. Although MOF is expressed in both males and females, it associates with the X chromosome only in males. MOF contains a zinc-finger domain that is used to contact the globular part of the nucleosome and histone H4. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone

Research_area:Others

Target_protein:MYST1

applications:WB, IHC, ICC

Reactivity:Human

Clonality:Monoclonal

Clone ID:8C4C4

Host:Mouse

Isotype:Mouse IgG2b

Gene Symbol/ Name:MYST1

Immunogen:Purified recombinant fragment of human MYST1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):53kDa

UniProt accession:Q9H7Z6

Synonyms:MOF, KAT8, hMOF

GeneID:84148