MYH Polyclonal Antibody

SKU: BT-AP05687

Size:100μL

Background:MUTYH encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. A/G-specific adenine DNA glycosylase is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:MUTYH

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:MYH Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):60069

UniProt accession:Human: Q9UIF7; Mouse: Q99P21; Rat: Q8R5G2

Synonyms:MUTYH; MYH; A/G-specific adenine DNA glycosylase; MutY homolog; hMYH

GeneID:Human: 4595; Mouse: 70603; Rat: 170841