MUC4 Polyclonal Antibody

SKU: BT-AP11575

Size:100μL

Background:The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats.

Research_area:Cancer; Signal transduction; Microbiology

Target_protein:MUC4

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Mucin-4

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q99102; Mouse: Q8JZM8; Rat: Q63661

Synonyms:Mucin-4 ;MUC-4;Ascites sialoglycoprotein;ASGP;Pancreatic adenocarcinoma mucin;Testis mucin;Tracheobronchial mucin [Cleaved into: Mucin-4 alpha chain ;Ascites sialoglycoprotein 1;ASGP-1;

GeneID:Human: 4585