MT-ND1 Antibody - Cat. #: CSB-PA149107

SKU: CSB-PA149107

Size :50ul

Clone Number:

Aliases:Complex I; subunit ND1 antibody; Mitochondrially encoded NADH dehydrogenase 1 antibody; MT-ND1 antibody; MTND1 antibody; NAD1 antibody; NADH dehydrogenase subunit 1 (complex I) antibody; NADH dehydrogenase subunit 1 antibody; NADH-ubiquinone oxidoreductase chain 1 antibody; NADH-ubiquinone oxidoreductase; subunit ND1 antibody; NADH1 antibody; ND1 antibody; NU1M_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P03886

Immunogen:Synthetic peptide of Human MT-ND1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200

Background:NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 1 (ND1) binds rotenone and rotenone analogs and might be involved in electron transfer to ubiquinone. Mutations in the ND1 gene may be implicated in several disorders, including Leber hereditary optic neuropathy, Alzheimer disease, and Parkinson disease.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MT-ND1

Research Areas:Cancer;Metabolism;Signal transduction