MSLN Rabbit Polyclonal Antibody

SKU: BT-AP11386

Size:100μL

Background:This gene encodes a preproprotein that is proteolytically processed to generate two protein products| megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas| ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants| at least one of which encodes an isoform that is proteolytically processed.

Research_area:Cancer; Tags & cell markers; Epigenetics and nuclear signaling

Target_protein:MSLN

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:MSLN

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):69300

UniProt accession:Human: Q13421; Mouse: Q61468; Rat: Q9ERA7

Synonyms:MSLN; Mesothelin; CAK1 antigen; Pre-pro-megakaryocyte-potentiating factor; Megakaryocyte-potentiating factor; MPF; Mesothelin; cleaved form;

GeneID:Human: 10232; Mouse: 56047; Rat: 60333