MSH3 Antibody - Cat. #: CSB-PA024849

SKU: CSB-PA024849

Size :50ul

Clone Number:

Aliases:Divergent upstream protein antibody; DNA mismatch repair protein antibody; DNA mismatch repair protein Msh 3 antibody; DNA mismatch repair protein MSH3 antibody; DUC 1 antibody; DUC1 antibody; DUG antibody; DUP antibody; hMSH3 antibody; MGC163306 antibody; MGC163308 antibody; Mismatch repair protein 1 antibody; MRP 1 antibody; MRP1 antibody; MSH 3 antibody; MSH3 antibody; MSH3_HUMAN antibody; MutS homolog 3 (E. coli) antibody; MutS homolog 3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P20585

Immunogen:Fusion protein of Human MSH3

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:10-1:50

Background:The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MSH3

Research Areas:Epigenetics and Nuclear Signaling