MRP-S22 Polyclonal Antibody

SKU: BT-AP05607

Size:100μL

Background:28S ribosomal protein S22 mitochondrial (mitochondrial ribosomal protein S22) is encoded by nuclear genes MRPS22 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:MRPS22

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Monkey

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:MRP-S22 Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):41280

UniProt accession:Human: P82650; Mouse: Q9CXW2

Synonyms:MRPS22; C3orf5; RPMS22; GK002; 28S ribosomal protein S22; mitochondrial; MRP-S22; S22mt

GeneID:Human: 56945