MPZ Antibody - Cat. #: CSB-PA571057

SKU: CSB-PA571057

Size :50ul

Clone Number:

Aliases:Charcot Marie Tooth neuropathy 1B antibody; CHM antibody; CMT1 antibody; CMT1B antibody; CMT2I antibody; CMT2J antibody; CMT4E antibody; CMTDI3 antibody; CMTDID antibody; DSS antibody; HMSNIB antibody; MPP antibody; MPZ antibody; Myelin peripheral protein antibody; Myelin protein P0 antibody; Myelin protein zero antibody; MYP0_HUMAN antibody; P0 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P25189

Immunogen:Fusion protein of Human MPZ

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:15-1:50

Background:This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. The P0 glycoprotein, absent in the central nervous system,[1] is a major component of the myelin sheath in peripheral nerves. It comprises a large extracellular N-terminal domain, a single transmembrane (TM) region, and a smaller positively charged intracellular domain.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MPZ

Research Areas:Neuroscience