Mouse Transcription Factor SOX 18,SOX18 ELISA KIT

SKU: E0910Mo

Size:96 Tests-1 Kit

Background:Transcriptional activator that binds to the consensus sequence 5'-AACAAAG-3' in the promoter of target genes and plays an essential role in embryonic cardiovascular development and lymphangiogenesis (PubMed:7651823, PubMed:10742113, PubMed:12748961, PubMed:18931657, PubMed:19429912, PubMed:26939885). Activates transcription of PROX1 and other genes coding for lymphatic endothelial markers (PubMed:18931657, PubMed:26939885). Plays an essential role in triggering the differentiation of lymph vessels, but is not required for the maintenance of differentiated lymphatic endothelial cells (PubMed:18931657). Plays an important role in postnatal angiogenesis, where it is functionally redundant with SOX17 (PubMed:16895970). Interaction with MEF2C enhances transcriptional activation (PubMed:11554755). Besides, required for normal hair development (PubMed:11094083, PubMed:12748961). {ECO:0000269|PubMed:10742113, ECO:0000269|PubMed:11094083, ECO:0000269|PubMed:11554755, ECO:0000269|PubMed:12748961, ECO:0000269|PubMed:16895970, ECO:0000269|PubMed:18931657, ECO:0000269|PubMed:19429912, ECO:0000269|PubMed:26939885, ECO:0000269|PubMed:7651823}.

Research_area:

Applications:ELISA

Target_protein:Sox18

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:43.55pg/ml

Detection range:100-6400pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Transcription Factor SOX 18

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P43680

MASS(Da):40898

GeneID:20672

Synonyms:Sox18 Sox-18

Gene names:Sox18

Standard solution:12800pg/ml