Mouse TIMP-1 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ0521

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: TIMP1

Specificity: Natural and recombinant mouse TIMP-1

Background: TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. It was found to reside at Xp11.4-p11.1. This is the first growth factor found to be X-linked. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. What’s more, TIMP1 is thought to play a regulatory role in connective tissues by forming inactive complexes with those metalloproteinases that are normally responsible for connective tissue turnover.

Immunogen: Expression system for standard: NS0; Immunogen sequence: C25-R205

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Uniprot ID: P12032

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 21857

Protein Name: Metalloproteinase inhibitor 1

Gene Full Name: tissue inhibitor of metalloproteinase 1

Synonyms: CLGI; Collagenase inhibitor; EPA; EPO; HCI; Metalloproteinase inhibitor 1; TIMP; TIMP 1; TIMP1; TIMP-1