Mouse Soluble Endoglin,sENG ELISA KIT

SKU: E0232Mo

Size:96 Tests-1 Kit

Background:Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis (PubMed:10625534). Required for normal structure and integrity of adult vasculature (By similarity). Regulates the migration of vascular endothelial cells (PubMed:17540773). Required for normal extraembryonic angiogenesis and for embryonic heart development (PubMed:10625534). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (PubMed:28530658). May play a role in the binding of endothelial cells to integrins. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors (PubMed:23300529). Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3 (By similarity). {ECO:0000250|UniProtKB:P17813, ECO:0000269|PubMed:10625534, ECO:0000269|PubMed:17540773, ECO:0000269|PubMed:23300529, ECO:0000269|PubMed:28530658}.

Research_area:

Applications:ELISA

Target_protein:Eng

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:23ng/ml

Detection range:50-3200ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Soluble Endoglin

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q63961

MASS(Da):70021

GeneID:13805

Synonyms:Eng Edg

Gene names:Eng

Standard solution:6400ng/ml