Mouse Pr Domain Zinc Finger Protein 16, PRDM16 ELISA Kit

SKU: E2358Mo

Size:96 Tests-1 Kit

Background:Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs (PubMed:27102484). Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection (PubMed:27102484). Binds specifically to the PRDI element in the promoter of the beta-interferon gene (By similarity). Drives the maturation of B-lymphocytes into Ig secreting cells (By similarity). Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions (PubMed:27102484).

Research_area:Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:PRDM16

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:5.22ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:PR domain zinc finger protein 16

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q60636

MASS(Da):95,836

GeneID:12142

Synonyms:B lymphocyte-induced maturation protein 1;b2b1765C;b2b1765Clo;Beta-interferon gene positive regulatory domain I-binding factor;Bli;Blim;Blimp1;Blimp-1;PR domain zinc finger protein 1;PR domain-containing protein 1;PRDI-;PRDI-BF1;PRDM16;

Gene names:Prdm1

Standard solution:2400ng/L