Mouse PLA2G2A ELISA Kit PicoKine®

SKU: EK1945

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Pla2g2a

Specificity: Natural and recombinant mouse PLA2G2A

Background: Phospholipase A2, membrane associated is an enzyme that in humans is encoded by the PLA2G2A gene. It is mapped to 4 D3; 4 70.57 cM. Proteins belonging to the phospholipase A2 (PLA2) family hydrolyze phospholipids into sn2 fatty acids and lysophospholipids. They function in a variety of cellular processes, including the digestion of phospholipids and the production of molecules that induce inflammatory responses. This gene encodes a member of the group II class of secretory PLA2s. The secreted enzyme binds to heparin on the cell surface. Mutations in this gene increase the occurrence of intestinal polyps caused by a dominant mutation in the adenomatosis polyposis coli gene. A frameshift inactivates this gene product in some mouse strains including the strain of the reference genome, C57BL/6J, whereas a functional protein is produced in other strains.

Immunogen: Expression system for standard: NS0; Immunogen sequence: N22-C146

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Reference:

Uniprot ID: P31482

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 18780

Protein Name: Phospholipase A2, membrane associated

Gene Full Name: phospholipase A2, group IIA (platelets, synovial fluid)

Synonyms: Phospholipase A2; membrane associated; Enhancing factor; EF; GIIC sPLA2; Group IIA phospholipase A2; Phosphatidylcholine 2-acylhydrolase 2A; Pla2g2a