Mouse Methionine Synthase, MTR ELISA Kit

SKU: E2670Mo

Size:96 Tests-1 Kit

Background:Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.

Research_area:Others

Applications:ELISA

Target_protein:MTR

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.015ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Methionine Synthase

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:A6H5Y3

MASS(Da):139,069

GeneID:238505

Synonyms:5-methyltetrahydrofolate--homocysteine methyltransferase;AI894170;Cobalamin-dependent methionine Synthase;D830038K18Rik;Methionine Synthase;MS;MTR;Vitamin-B12 dependent methionine Synthase

Gene names:Mtr

Standard solution:24ng/ml