Mouse Matrix Metalloproteinase-14, MMP14 ELISA Kit

SKU: E2238Mo

Size:96 Tests-1 Kit

Background:Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (PubMed:10520996). May be involved in actin cytoskeleton reorganization by cleaving PTK7 (By similarity). Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues (By similarity). Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (By similarity).

Research_area:Cardiovascular; Signal Transduction; Cancer; Cell Biology

Applications:ELISA

Target_protein:MMP14

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.022ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Matrix Metalloproteinase-14

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P53690

MASS(Da):65,919

GeneID:17387

Synonyms:AI325305;Matrix Metalloproteinase-14;Membrane-type Matrix Metalloproteinase 1;Membrane-type-1 Matrix Metalloproteinase;MMP14;MMP-14;MMP-X1;MT1-MM;MT1MMP;MT1-MMP;MT-MMP;MT-MMP 1;MTMMP1;sa;sabe

Gene names:Mmp14

Standard solution:24ng/mL