Mouse KIM1/TIM1 PicoKine® Quick ELISA Kit

SKU: FEK0880

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: CST3

Specificity: Natural and recombinant Mouse Havcr1

Background: KIM1 (TIM-1), also known as Hepatitis A virus cellular receptor 1, is a protein that in Mouses is encoded by the HAVCR1 gene. Infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV led Feigelstock et al. (1998) to conclude that the protein is indeed a receptor for the virus. Immunofluorescence microscopy demonstrated internalization of HAV by dog cells expressing HAVCR1. Using a monoclonal antibody to mouse Tim1, Umetsu et al. (2005) showed that Tim1 was expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. By homology of synteny with the mouse Tim1 gene and database analysis, McIntire et al. (2001) mapped the HAVCR1 gene to 5q33.2. The standard used in this kit is recombinant mouse KIM-1, constituting from Y22-T212 amino acids, and 191amino acids with the molecular mass of 21.8KDa.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Y22-T212

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Uniprot ID: Q5QNS5

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 171283

Protein Name: Hepatitis A virus cellular receptor 1 homolog

Gene Full Name: hepatitis A virus cellular receptor 1

Synonyms: hepatitis A virus cellular receptor 1; CD365; HAVCR; HAVCR-1; KIM-1; KIM1; TIM; TIM-1; TIM1; TIMD-1; TIMD1; HAVCR1