GeneBio Systems
Mouse JAM-A / F11R / Junctional Adhesion Molecule 1 ELISA Kit PicoKine®
Mouse JAM-A / F11R / Junctional Adhesion Molecule 1 ELISA Kit PicoKine®
SKU:EK1228
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Size: 96 wells/kit, with removable strips.
Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Form:
Reactivity: Mouse
Applications: ELISA
Application Details:
Gene Name: F11R
Specificity: Natural and recombinant mouse JAM-A
Background: Junctional adhesion molecule A (JAM-A) is a protein that in humans is encoded by the F11R gene. It is mapped to 1q23.3. This gene is an immunoglobulin-like molecule that colocalizes with tight junctions in endothelium and epithelium and is also found on blood leukocytes and platelets. JAM-A plays an important role in the regulation of tight junction assembly in epithelia. In addition, it can act as a receptor for reovirus, a ligand for the integrin LFA1, involved in leukocyte transmigration, and a platelet receptor. JAM-A has a nonredundant role in controlling DC motility, trafficking to lymph nodes, and activation of specific immunity.
Immunogen: Expression system for standard: NS0; Immunogen sequence: K27-G238
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Reference:
Uniprot ID: O88792
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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.
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Gene ID: 16456
Protein Name: Junctional adhesion molecule A
Gene Full Name: F11 receptor
Synonyms: CD321; F11 receptor; F11R; JAM; JAM 1; JAM A; JAM1; JAMA; JAMA1; JCAM; Junctional adhesion molecule 1; Junctional adhesion molecule A; KAT; PAM 1; Platelet adhesion molecule 1; Platelet F11 receptor
