Mouse Interleukin 21, IL-21 ELISA Kit

SKU: E0614Mo

Size:96 Tests-1 Kit

Background:Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (PubMed: 15100251). Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers. Together with IL6, control the early generation of Tfh cells and are critical for an effective antibody response to acute viral infection (PubMed: 23045607). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15 (PubMed: 11970879). May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (By similarity). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation (PubMed: 12893770).

Research_area:Immunology; Cancer

Applications:ELISA

Target_protein:IL21

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:4.55ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Interleukin 21

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9ES17

MASS(Da):16,811

GeneID:60505

Synonyms:IL 21;IL21;IL-21;Interleukin-21

Gene names:IL21

Standard solution:2400ng/L