Mouse Interferon Regulatory Factor 5, IRF5 ELISA Kit

SKU: E2163Mo

Size:96 Tests-1 Kit

Background:Transcription factor that plays a critical role in innate immunity by activating expression of type I interferon (IFN) IFNA and INFB and inflammatory cytokines downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9 (PubMed:15665823). Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters (PubMed:15665823). Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction downstream of the TLR-activated, MyD88-dependent pathway (PubMed:15665823).

Research_area:Immunology; Epigenetics and Nuclear Signaling

Applications:ELISA

Target_protein:IRF5

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:1.54ng/L

Detection range:3-900ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:interferon regulatory factor 5

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P56477

MASS(Da):56,005

GeneID:27056

Synonyms:AW491843;Interferon regulatory factor 5;IRF 5;IRF5;IRF-5;mir;mirf5

Gene names:Irf5

Standard solution:960ng/L